Vol. 11, Issue 1, Part B (2024)

Introduction: Malaria and Dengue are two vector borne diseases having gained a major concerns worldwide, particularly in tropical and subtropical region owing to their recurring outbreaks. Mosquito bite is considered to be the major cause they are transmitted to human by the bite of mosquito and cause different hematological manifestation.

Aim: To compare the laboratory features and outcome of mono-infection or co-infection with both Malaria and Dengue infections.

Materials and Methods: 256 suspected patients were tested for Malaria and Dengue infections. Serological diagnosis of dengue was done using rapid dengue duo kit which detects Ns1, IgM and IgG. Malarial parasite were identified by peripheral blood smear (thick and thin), rapid test were performed by Sure Test Malaria PF/PV HRP2/pLdh Combo kit which detects plasmodium falciparum and plasmodium vivax by using human blood.

Results: Of the 256 cases, most affected age group was 19-35 years (77%) and the less affected age group was >56 years (23%) while male and female ratio is 1:1. Of the 256 cases, 128 were dengue seropositive cases, 2 of which were Malaria positive and 1 case was showed co-infection. We observed that hematological parameters like hemoglobin, platelet count, SGPT and total leucocyte count were significantly higher in both Dengue and Malaria.

Conclusion: This study concluded that all patients presented with the febrile illness should be tested for both Malaria and Dengue. Both presented with similar clinical manifestations which is why specific diagnostic testing along with complete blood count is necessary to confirm the diagnosis and to know the severity of the illness.