Vol. 10, Issue 5, Part A (2023)

Mosquito-borne diseases are a major public health concern worldwide. Plant extracts from Andrographis paniculata have anti-mosquito properties. The study evaluated the extracts' larvicidal, pupicidal, and ovicidal activities, and their LC₅₀ values were compared between the two mosquito species to determine their relative effectiveness in controlling mosquito populations. The study shows that methanol extracts have promising larvicidal, pupicidal, and ovicidal activities against Aedes Aegypti and Culex quinquefasciatus mosquito species. Methanol extracts showed promising larvicidal, pupicidal, and ovicidal activities against Ae. Aegypti and Cx. quinquefasciatus species with LC₅₀ values of 86.74 and 84.41 ppm for larvicidal activity, 95.27 and 92.91 ppm for pupicidal activity, and 56.8 and 60.0 ppm for ovicidal activity, respectively. Hexane and chloroform extracts showed good larvicidal activity but not promising pupicidal and ovicidal activities. Further research is needed to determine the active compounds and evaluate their safety and efficacy in the field.