Vol. 9, Issue 2, Part B (2022)

Author(s): Manoj Singh, Sushil Kumar Upadhyay, Shivani Gupta, Vanita Thakur and Anil Kumar Sharma

Abstract: There are many vector–borne illnesses known to be spread by the mosquito Aedes aegypti Linn. (Diptera: Culicidae), which kills millions of people each year worldwide. There is no vaccination available for A. aegypti–transmitted viral diseases so far. As a result, it is imperative to control the mosquitoes or vector population which may helpful to avoid the dispersal and causes of certain diseases. The most common and conventional mechanism to control mosquitoes population are physical, biological, and chemical control measures that have all been used to prevent Aedes species borne disease spreading. Among these the most effective method is chemical control method but it results into the environmental pollution and causes damage to non–target individuals as well. A manipulation through self–limiting using genetic engineering among mosquitoes is an effective substitute to one sex for the control of insect pests. Using the modern concept of gene manipulation, the lethal gene through an antidote (tetracycline) was repressed among male mosquitos in vitro and subsequently released in the natural environment to mate with normal female and give rise filial generation which will die during larval stage due to lack of tetracycline. The most profound and recent use of nanotechnology to generate more effective and less dangerous repellent and larvicidal compositions is another strategy under investigation. The development of novel nanotechnology–based formulations for containing natural and synthetic repellents is an important step toward more effective systems with fewer adverse side effects.

DOI: 10.22271/23487941.2022.v9.i2b.604