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International Journal of Mosquito Research
Vol. 7, Issue 4, Part B (2020)
A review: mosquito proteomics and its potential role in insecticide resistance detection
Author(s): Shettima A, Ishak IH, Abu Hasan H and Othman N
Abstract: Vector control remains the best technique to fight mosquito-borne infections worldwide, and it is an essential entity of a global strategy for the management of mosquito-borne diseases. Insecticide continues to be the widely used method to achieve vector eradication and elimination. However, the increased use of insecticide has contributed to the establishment of resistance, jeopardizing the effectiveness of control methods globally. The outcome of the resistance is the enormous human and economic loss. The use of mosquito proteome analyses to identify the expression of the whole complement of proteins in a cell or organism at a particular moment, and in response to various physiological changes and stress, has indeed revealed so much of protein behaviors. This paper reviews the scenario and mechanisms of insecticide resistance in mosquitoes and also highlighted proteins associated with insecticide resistance compared to susceptible mosquito strains under different physiological states. Differentially expressed proteins hold the key in elucidating resistant patterns and possible development of biomarkers in predicting resistance in field strain mosquitoes as well as surveillance for control strategies.
How to cite this article:
Shettima A, Ishak IH, Abu Hasan H, Othman N. A review: mosquito proteomics and its potential role in insecticide resistance detection. Int J Mosq Res 2020;7(4):112-117.