Spectrum of renal dysfunction in malaria

Authors: Nitesh Chandra Toshan, Vijay Kumar Tundwal, Vinod Kumar Aswal, Narendra Kumar Gahlot, Manoj Kumar Meena, Sanjay Kumar Kochar
Out of 19053 fever cases screened for malaria, 509 cases were found positive for malaria and 284 cases were selected for the present study. Total 31 patients had renal failure. 70.97% of renal failure patient had P. vivax mono-infection. Thrombocytopenia was the most common hematological abnormality. 7 (22.58% of malarial renal failure) patients required hemodialysis. All patients had vivax malaria. 5 patients’ health improved after hemodialysis while 2 patients died during the course of illness. 5 patients (1.76%) died during the hospitalization, out of which, 4 patients had renal failure. Previously vivax malaria was considered as a benign disease, but now all sort of complications of malaria also have been observed with P. vivax infection. Although the significant number of patients were improved conservatively with anti-malarial drugs but the availability of renal replacement therapy for malarial renal failure has been shown to improve outcome.

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