Vol. 2, Issue 4, Part A (2015)

Author(s): Amrutha Chacko, Priscilla Helen Christy, Kavya KS

Abstract: The present study was conducted to identify the larvicidal activity of Ruta graveolens against larval cultures of Anopheles stephensi and Aedes aegypti. The larvicidal bioassay of each plant extract was conducted. The % of mortality was calculated. The petroleum ether extract showed maximum larvicidal activity against both the larvae when compared to the hexane and methanol extract. The petroleum ether extract was then subjected to TLC using the solvent system petroleum ether: chloroform: acetone at 0.5: 1.5: 0.5 ratios. The larvicidal activity of the pure compound was checked and the % mortality of different fractions was calculated. It was observed that the fraction 1 showed 100% mortality against An. stephensi and 80% mortality against Ae. aegypti and toxicity was not observed for the cream prepared for fraction 1. The functional groups were analyzed using FTIR analysis.

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